STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRL39053.1Cell division protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. (94 aa)    
Predicted Functional Partners:
KRL39057.1
Multimodular transpeptidase-transglycosylase PBP 1A.
 
 
 
 0.947
KRL38585.1
Multimodular transpeptidase-transglycosylase PBP 2A.
   
 
 0.875
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
 
 0.849
recU
Holliday junction-specific endonuclease; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
 
   
 0.832
KRL38659.1
Serine threonine protein kinase.
 
 
 0.808
KRL38640.1
Penicillin-binding protein.
 
  
 0.747
divIB
Cell division protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
   
 0.710
KRL38502.1
Hypothetical protein.
  
     0.689
KRL38405.1
Hypothetical protein.
  
     0.685
KRL39086.1
Rod shape-determining protein MreD.
  
   
 0.675
Your Current Organism:
Lactobacillus uvarum
NCBI taxonomy Id: 1423812
Other names: L. uvarum DSM 19971, Lactobacillus sp. 8, Lactobacillus uvarum DSM 19971
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.