STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRL33271.1Membrane alanine aminopeptidase. (844 aa)    
Predicted Functional Partners:
KRL36761.1
Xaa-His dipeptidase.
   
 0.949
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.926
KRL39099.1
Bifunctional glutamate--cysteine ligase glutathione synthetase; Belongs to the glutamate--cysteine ligase type 1 family.
     
 0.898
KRL38440.1
Cysteine synthase.
    
 0.809
KRL37852.1
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.809
KRL36767.1
Glutathione synthase; Belongs to the glutamate--cysteine ligase type 1 family.
     
 0.803
gshAB
Bifunctional glutamate--cysteine ligase glutathione synthetase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
     
 0.803
KRL32884.1
coA-disulfide reductase.
    
  0.795
pepX
X-prolyl-dipeptidyl aminopeptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family.
 
   
 0.730
KRL36814.1
Cystathionine beta-lyase.
     
 0.724
Your Current Organism:
Lactobacillus uvarum
NCBI taxonomy Id: 1423812
Other names: L. uvarum DSM 19971, Lactobacillus sp. 8, Lactobacillus uvarum DSM 19971
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