STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM62121.1Thiol-disulfide isomerase and thioredoxin. (106 aa)    
Predicted Functional Partners:
KRM61297.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 0.989
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.983
KRM61200.1
Hypothetical protein.
   
 0.900
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 0.864
KRM60692.1
Glutathione reductase.
  
 0.860
KRM62592.1
Glutathione reductase.
  
 0.860
KRM62366.1
Dihydrolipoamide dehydrogenase.
  
 0.860
KRM60471.1
Thioredoxin reductase (NADPH).
  
 0.848
KRM61632.1
Thioredoxin reductase.
   
 0.844
KRM62536.1
Putative NADH oxidase (putative).
   
 0.844
Your Current Organism:
Lactobacillus vaccinostercus
NCBI taxonomy Id: 1423813
Other names: L. vaccinostercus DSM 20634, Lactobacillus vaccinostercus DSM 20634
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.