node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEJ40701.1 | EEJ40702.1 | HMPREF0549_0799 | HMPREF0549_0800 | CobB/CobQ-like protein; COG: COG3442. | Mur ligase middle domain protein; COG: COG0769. | 0.999 |
EEJ40701.1 | murE | HMPREF0549_0799 | HMPREF0549_1065 | CobB/CobQ-like protein; COG: COG3442. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.937 |
EEJ40701.1 | murG | HMPREF0549_0799 | HMPREF0549_0190 | CobB/CobQ-like protein; COG: COG3442. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.929 |
EEJ40702.1 | EEJ40701.1 | HMPREF0549_0800 | HMPREF0549_0799 | Mur ligase middle domain protein; COG: COG0769. | CobB/CobQ-like protein; COG: COG3442. | 0.999 |
EEJ40702.1 | divIB | HMPREF0549_0800 | HMPREF0549_0191 | Mur ligase middle domain protein; COG: COG0769. | Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | 0.501 |
EEJ40702.1 | mraY | HMPREF0549_0800 | HMPREF0549_0188 | Mur ligase middle domain protein; COG: COG0769. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.762 |
EEJ40702.1 | murC | HMPREF0549_0800 | HMPREF0549_1642 | Mur ligase middle domain protein; COG: COG0769. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.688 |
EEJ40702.1 | murD | HMPREF0549_0800 | HMPREF0549_0189 | Mur ligase middle domain protein; COG: COG0769. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.881 |
EEJ40702.1 | murF | HMPREF0549_0800 | HMPREF0549_0074 | Mur ligase middle domain protein; COG: COG0769. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.901 |
EEJ40702.1 | murG | HMPREF0549_0800 | HMPREF0549_0190 | Mur ligase middle domain protein; COG: COG0769. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.976 |
EEJ41349.1 | divIB | HMPREF0549_0225 | HMPREF0549_0191 | Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772; Belongs to the SEDS family. | Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | 0.857 |
EEJ41349.1 | ftsZ | HMPREF0549_0225 | HMPREF0549_0193 | Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772; Belongs to the SEDS family. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.800 |
EEJ41349.1 | mraY | HMPREF0549_0225 | HMPREF0549_0188 | Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.870 |
EEJ41349.1 | murC | HMPREF0549_0225 | HMPREF0549_1642 | Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772; Belongs to the SEDS family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.871 |
EEJ41349.1 | murD | HMPREF0549_0225 | HMPREF0549_0189 | Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.893 |
EEJ41349.1 | murE | HMPREF0549_0225 | HMPREF0549_1065 | Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.684 |
EEJ41349.1 | murF | HMPREF0549_0225 | HMPREF0549_0074 | Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.837 |
EEJ41349.1 | murG | HMPREF0549_0225 | HMPREF0549_0190 | Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772; Belongs to the SEDS family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.953 |
divIB | EEJ40702.1 | HMPREF0549_0191 | HMPREF0549_0800 | Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | Mur ligase middle domain protein; COG: COG0769. | 0.501 |
divIB | EEJ41349.1 | HMPREF0549_0191 | HMPREF0549_0225 | Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772; Belongs to the SEDS family. | 0.857 |