node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEJ40060.1 | EEJ41177.1 | HMPREF0549_1471 | HMPREF0549_0390 | Oxidoreductase, NAD-binding domain protein; COG: COG0673. | Aldose 1-epimerase; COG: COG2017. | 0.650 |
EEJ40060.1 | agaR | HMPREF0549_1471 | HMPREF0549_0036 | Oxidoreductase, NAD-binding domain protein; COG: COG0673. | Alpha-galactosidase; COG: COG3345. | 0.523 |
EEJ40060.1 | galE | HMPREF0549_1471 | HMPREF0549_0707 | Oxidoreductase, NAD-binding domain protein; COG: COG0673. | UDP-glucose 4-epimerase; COG: COG1087; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | 0.636 |
EEJ40060.1 | galK | HMPREF0549_1471 | HMPREF0549_1163 | Oxidoreductase, NAD-binding domain protein; COG: COG0673. | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. | 0.866 |
EEJ40937.1 | EEJ41177.1 | HMPREF0549_0615 | HMPREF0549_0390 | Phage integrase SAM-like domain protein; COG: COG4974; Belongs to the 'phage' integrase family. | Aldose 1-epimerase; COG: COG2017. | 0.522 |
EEJ40937.1 | topA | HMPREF0549_0615 | HMPREF0549_0389 | Phage integrase SAM-like domain protein; COG: COG4974; Belongs to the 'phage' integrase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.695 |
EEJ41177.1 | EEJ40060.1 | HMPREF0549_0390 | HMPREF0549_1471 | Aldose 1-epimerase; COG: COG2017. | Oxidoreductase, NAD-binding domain protein; COG: COG0673. | 0.650 |
EEJ41177.1 | EEJ40937.1 | HMPREF0549_0390 | HMPREF0549_0615 | Aldose 1-epimerase; COG: COG2017. | Phage integrase SAM-like domain protein; COG: COG4974; Belongs to the 'phage' integrase family. | 0.522 |
EEJ41177.1 | EEJ41265.1 | HMPREF0549_0390 | HMPREF0549_0309 | Aldose 1-epimerase; COG: COG2017. | HAD hydrolase, TIGR02254 family; COG: COG1011. | 0.627 |
EEJ41177.1 | agaR | HMPREF0549_0390 | HMPREF0549_0036 | Aldose 1-epimerase; COG: COG2017. | Alpha-galactosidase; COG: COG3345. | 0.518 |
EEJ41177.1 | galE | HMPREF0549_0390 | HMPREF0549_0707 | Aldose 1-epimerase; COG: COG2017. | UDP-glucose 4-epimerase; COG: COG1087; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | 0.700 |
EEJ41177.1 | galK | HMPREF0549_0390 | HMPREF0549_1163 | Aldose 1-epimerase; COG: COG2017. | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. | 0.960 |
EEJ41177.1 | gph | HMPREF0549_0390 | HMPREF0549_1175 | Aldose 1-epimerase; COG: COG2017. | Glycoside/pentoside/hexuronide transporter. | 0.751 |
EEJ41177.1 | manA | HMPREF0549_0390 | HMPREF0549_0419 | Aldose 1-epimerase; COG: COG2017. | Mannose-6-phosphate isomerase, class I; COG: COG1482; Belongs to the mannose-6-phosphate isomerase type 1 family. | 0.546 |
EEJ41177.1 | topA | HMPREF0549_0390 | HMPREF0549_0389 | Aldose 1-epimerase; COG: COG2017. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.729 |
EEJ41177.1 | zwf | HMPREF0549_0390 | HMPREF0549_1177 | Aldose 1-epimerase; COG: COG2017. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.556 |
EEJ41265.1 | EEJ41177.1 | HMPREF0549_0309 | HMPREF0549_0390 | HAD hydrolase, TIGR02254 family; COG: COG1011. | Aldose 1-epimerase; COG: COG2017. | 0.627 |
EEJ41265.1 | gph | HMPREF0549_0309 | HMPREF0549_1175 | HAD hydrolase, TIGR02254 family; COG: COG1011. | Glycoside/pentoside/hexuronide transporter. | 0.532 |
EEJ41265.1 | manA | HMPREF0549_0309 | HMPREF0549_0419 | HAD hydrolase, TIGR02254 family; COG: COG1011. | Mannose-6-phosphate isomerase, class I; COG: COG1482; Belongs to the mannose-6-phosphate isomerase type 1 family. | 0.535 |
agaR | EEJ40060.1 | HMPREF0549_0036 | HMPREF0549_1471 | Alpha-galactosidase; COG: COG3345. | Oxidoreductase, NAD-binding domain protein; COG: COG0673. | 0.523 |