STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pncB-2Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (476 aa)    
Predicted Functional Partners:
cinA
Competence/damage-inducible domain protein CinA; COG: COG1058; Belongs to the CinA family.
  
 
 0.963
EEJ40100.1
Isochorismatase family protein; COG: COG1335.
  
 
 0.950
nadD-2
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.888
nadD
Nicotinate-nucleotide adenylyltransferase; COG: COG1057.
  
 
 0.886
lytB
Cell wall-binding repeat protein.
    
  0.822
EEJ40098.1
Hydrolase, NUDIX family; COG: COG1051.
 
  
 0.766
EEJ41519.1
Transcriptional regulator, Sir2 family; COG: COG0846.
  
 0.661
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
  
 
 0.654
EEJ39875.1
Hydrolase, HD family; COG: COG1713.
     
 0.560
EEJ41331.1
Tetratricopeptide repeat protein.
  
  0.520
Your Current Organism:
Lactobacillus vaginalis
NCBI taxonomy Id: 1423814
Other names: L. vaginalis DSM 5837 = ATCC 49540, Lactobacillus vaginalis ATCC 49540, Lactobacillus vaginalis ATCC 49540 = DSM 5837, Lactobacillus vaginalis DSM 5837, Lactobacillus vaginalis DSM 5837 = ATCC 49540
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.