STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRK99335.1Hypothetical protein. (208 aa)    
Predicted Functional Partners:
KRK92414.1
Pyrophosphatase ppaX.
 
 
  0.911
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
  0.893
KRK93539.1
CinA domain-containing protein; Belongs to the CinA family.
    
 0.886
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
     
 0.871
KRK99334.1
Hypothetical protein.
  
 
  0.640
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.634
nrdJ
Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent.
 
  
  0.582
nfsA
Nitroreductase (oxidoreductase); Belongs to the flavin oxidoreductase frp family.
    
  0.561
KRK99037.1
Nucleoside triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
 0.543
plsY
Membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
  0.512
Your Current Organism:
Lactobacillus futsaii
NCBI taxonomy Id: 1423818
Other names: L. futsaii JCM 17355, Lactobacillus futsaii JCM 17355, Lactobacillus futsaii YM 0097, Lactobacillus sp. YM 0097
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