STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM51573.1IpaB EvcA family protein. (320 aa)    
Predicted Functional Partners:
KRM51572.1
3-hydroxy-3-methylglutaryl-coenzyme a reductase; Belongs to the HMG-CoA reductase family.
  
    0.842
KRM51574.1
Sir2 family transcriptional regulator.
  
    0.806
KRM51760.1
Hypothetical protein.
  
     0.742
KRM52593.1
Hypothetical protein.
  
     0.708
KRM52275.1
Hypothetical protein.
  
     0.701
KRM51796.1
Rod shape-determining protein mred.
  
     0.695
KRM51831.1
Hypothetical protein.
  
     0.664
mprF-2
Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
     0.641
metG
Methionyl-trna synthetase protein secretion chaperonin csaa; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
       0.624
KRM52749.1
Cro CI family transcriptional regulator.
  
     0.587
Your Current Organism:
Lactobacillus aviarius
NCBI taxonomy Id: 1423820
Other names: L. aviarius subsp. araffinosus DSM 20653, Lactobacillus aviarius subsp. araffinosus DSM 20653
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.