node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SER58804.1 | radA | SAMN04488559_10230 | SAMN04488559_107121 | ATP-dependent DNA helicase PcrA. | DNA replication and repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.712 |
SER58804.1 | recA | SAMN04488559_10230 | SAMN04488559_1048 | ATP-dependent DNA helicase PcrA. | Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.957 |
SER58804.1 | uvrC | SAMN04488559_10230 | SAMN04488559_10471 | ATP-dependent DNA helicase PcrA. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.745 |
SER84380.1 | SER84436.1 | SAMN04488559_107120 | SAMN04488559_107123 | Uncharacterized conserved protein YacL, contains PIN and TRAM domains. | Transcriptional regulator CtsR; Belongs to the CtsR family. | 0.657 |
SER84380.1 | gltX | SAMN04488559_107120 | SAMN04488559_107117 | Uncharacterized conserved protein YacL, contains PIN and TRAM domains. | Nondiscriminating glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.718 |
SER84380.1 | ispD | SAMN04488559_107120 | SAMN04488559_107119 | Uncharacterized conserved protein YacL, contains PIN and TRAM domains. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.885 |
SER84380.1 | ispF | SAMN04488559_107120 | SAMN04488559_107118 | Uncharacterized conserved protein YacL, contains PIN and TRAM domains. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.802 |
SER84380.1 | radA | SAMN04488559_107120 | SAMN04488559_107121 | Uncharacterized conserved protein YacL, contains PIN and TRAM domains. | DNA replication and repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.826 |
SER84420.1 | SER84436.1 | SAMN04488559_107122 | SAMN04488559_107123 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Transcriptional regulator CtsR; Belongs to the CtsR family. | 0.905 |
SER84420.1 | radA | SAMN04488559_107122 | SAMN04488559_107121 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | DNA replication and repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.550 |
SER84436.1 | SER84380.1 | SAMN04488559_107123 | SAMN04488559_107120 | Transcriptional regulator CtsR; Belongs to the CtsR family. | Uncharacterized conserved protein YacL, contains PIN and TRAM domains. | 0.657 |
SER84436.1 | SER84420.1 | SAMN04488559_107123 | SAMN04488559_107122 | Transcriptional regulator CtsR; Belongs to the CtsR family. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.905 |
SER84436.1 | ispD | SAMN04488559_107123 | SAMN04488559_107119 | Transcriptional regulator CtsR; Belongs to the CtsR family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.410 |
SER84436.1 | radA | SAMN04488559_107123 | SAMN04488559_107121 | Transcriptional regulator CtsR; Belongs to the CtsR family. | DNA replication and repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.542 |
gltX | SER84380.1 | SAMN04488559_107117 | SAMN04488559_107120 | Nondiscriminating glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Uncharacterized conserved protein YacL, contains PIN and TRAM domains. | 0.718 |
gltX | ispD | SAMN04488559_107117 | SAMN04488559_107119 | Nondiscriminating glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.727 |
gltX | ispF | SAMN04488559_107117 | SAMN04488559_107118 | Nondiscriminating glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.766 |
gltX | radA | SAMN04488559_107117 | SAMN04488559_107121 | Nondiscriminating glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | DNA replication and repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.652 |
gltX | recA | SAMN04488559_107117 | SAMN04488559_1048 | Nondiscriminating glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.671 |
ispD | SER84380.1 | SAMN04488559_107119 | SAMN04488559_107120 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | Uncharacterized conserved protein YacL, contains PIN and TRAM domains. | 0.885 |