STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SER97197.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (525 aa)    
Predicted Functional Partners:
SER97213.1
Pyruvate dehydrogenase E1 component beta subunit.
 0.991
SER97257.1
Dihydrolipoamide dehydrogenase.
 0.990
pdhA-2
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.989
SER76284.1
Dihydrolipoamide dehydrogenase.
 0.978
SER76255.1
Pyruvate dehydrogenase E1 component beta subunit.
 0.974
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.964
SER49575.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 
 0.961
SES01714.1
Branched-chain alpha-keto acid dehydrogenase E1 component.
 0.959
SER60599.1
Lipoate-protein ligase.
 
 0.952
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.949
Your Current Organism:
Isobaculum melis
NCBI taxonomy Id: 142588
Other names: CCUG 37660, DSM 13760, I. melis, Isobaculum melis Collins et al. 2002, strain M577-94
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