STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALF09454.1CRISPR-associated protein Cas6; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). (248 aa)    
Predicted Functional Partners:
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.912
ALF11995.1
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
   
 0.902
cas1
Subtype I-B CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.896
ALF09451.1
CRISPR-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.895
ALF09450.1
CRISPR-associated protein Cas5; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.886
ALF09449.1
CRISPR-associated protein Csd2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.867
ALF09448.1
CRISPR-associated protein Csh1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.831
ALF10769.1
CRISPR-associated protein Crm2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.668
ALF10771.1
CRISPR-associated protein Cmr4; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.645
ALF10767.1
CRISPR-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.543
Your Current Organism:
Parageobacillus thermoglucosidasius
NCBI taxonomy Id: 1426
Other names: ATCC 43742, BGSC 95A1, Bacillus sp. BGSC W9A92, Bacillus thermoglucosidasius, CCUG 28887, CIP 106930, DSM 2542, Geobacillus thermoglucosidans, Geobacillus thermoglucosidasius, LMG 7137, LMG:7137, NBRC 107763, NCIMB 11955, NRRL B-14516, P. thermoglucosidasius, Parageobacillus thermoglucosidans, strain R-35637
Server load: low (24%) [HD]