STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase. (433 aa)    
Predicted Functional Partners:
SJZ66494.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.996
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.994
SJZ66573.1
Uroporphyrinogen III methyltransferase / synthase.
 
 
 0.992
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.985
SJZ66655.1
Precorrin-2 dehydrogenase.
  
 0.976
SJZ55000.1
[Acyl-carrier-protein] S-malonyltransferase.
    
 0.918
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
    
 0.749
SJZ66415.1
Putative heme d1 biosynthesis radical SAM protein NirJ2.
  
 
 0.744
SJZ54856.1
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
  
 0.734
SJZ66363.1
Transcriptional regulator, AsnC family.
     
 0.715
Your Current Organism:
Selenihalanaerobacter shriftii
NCBI taxonomy Id: 142842
Other names: ATCC BAA-73, S. shriftii, Selenihalanaerobacter shriftii Switzer Blum et al. 2001, Selenohalobacter shriftii, strain DSSe-1
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