KIX14988.1 protein (Dethiosulfatarculus sandiegensis)

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

KIX14988.1

Secretion activator protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)

Predicted Functional Partners:

KIX15040.1

0.773

KIX15034.1

0.601

KIX15035.1

0.577

KIX14986.1

0.576

KIX15037.1

0.575

KIX14987.1

0.565

KIX14985.1

0.545

KIX15039.1

0.543

KIX14984.1

0.542

KIX15036.1

0.533

Your Current Organism:

Dethiosulfatarculus sandiegensis

NCBI taxonomy Id: 1429043
Other names: D. sandiegensis, DSM 100305, Deltaproteobacteria bacterium SPR, Desulfarculus sp. SPR, Dethiosulfatarculus sandiegensis Davidova et al. 2016, JCM 30857, strain SPR

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KIX14984.1	KIX14985.1	X474_05740	X474_05750	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.979
KIX14984.1	KIX14986.1	X474_05740	X474_05760	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
KIX14984.1	KIX14987.1	X474_05740	X474_05765	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Baseplate J protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
KIX14984.1	KIX14988.1	X474_05740	X474_05790	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Secretion activator protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.542
KIX14984.1	KIX15034.1	X474_05740	X474_05735	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.851
KIX14984.1	KIX15035.1	X474_05740	X474_05745	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.981
KIX14984.1	KIX15036.1	X474_05740	X474_05755	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.996
KIX14984.1	KIX15037.1	X474_05740	X474_05770	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.996
KIX14984.1	KIX15039.1	X474_05740	X474_05780	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.765
KIX14984.1	KIX15040.1	X474_05740	X474_05785	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.533
KIX14985.1	KIX14984.1	X474_05750	X474_05740	Baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.979
KIX14985.1	KIX14986.1	X474_05750	X474_05760	Baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
KIX14985.1	KIX14987.1	X474_05750	X474_05765	Baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Baseplate J protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.983
KIX14985.1	KIX14988.1	X474_05750	X474_05790	Baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Secretion activator protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.545
KIX14985.1	KIX15034.1	X474_05750	X474_05735	Baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.875
KIX14985.1	KIX15035.1	X474_05750	X474_05745	Baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.982
KIX14985.1	KIX15036.1	X474_05750	X474_05755	Baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.975
KIX14985.1	KIX15037.1	X474_05750	X474_05770	Baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.981
KIX14985.1	KIX15039.1	X474_05750	X474_05780	Baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.768
KIX14985.1	KIX15040.1	X474_05750	X474_05785	Baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.533

page 1 of 6

Network Stats

number of nodes:

5

number of edges:

10

average node degree:

4

avg. local clustering coefficient:

1

expected number of edges:

4

PPI enrichment p-value:

0.00533

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006418

tRNA aminoacylation for protein translation

5 of 23

1.94

2.9

3.38e-07

GO:0006412

Translation

9 of 114

1.5

2.64

5.14e-10

GO:0044271

Cellular nitrogen compound biosynthetic process

10 of 353

1.05

1.33

1.85e-08

GO:1901566

Organonitrogen compound biosynthetic process

10 of 445

0.95

1.09

1.61e-07

GO:0006520

Cellular amino acid metabolic process

6 of 217

1.04

0.96

0.00031

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140101

Catalytic activity, acting on a tRNA

8 of 41

1.89

4.15

1.49e-11

GO:0004812

aminoacyl-tRNA ligase activity

5 of 24

1.92

2.8

5.53e-07

GO:0050567

glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity

3 of 3

2.6

2.67

1.03e-05

GO:0016884

Carbon-nitrogen ligase activity, with glutamine as amido-N-donor

4 of 14

2.06

2.59

4.52e-06

GO:0016874

Ligase activity

9 of 129

1.44

2.49

4.20e-10

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:373

Aminoacyl-tRNA synthetase

4 of 14

2.06

2.09

6.43e-05

CL:389

phenylalanyl-tRNA aminoacylation, and Aminoacyl-tRNA synthetase

3 of 6

2.3

1.84

0.00033

CL:1494

Amine-lyase activity, and glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity

3 of 6

2.3

1.84

0.00033

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

psul00970

Aminoacyl-tRNA biosynthesis

8 of 24

2.12

5.57

5.72e-14

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030956

glutamyl-tRNA(Gln) amidotransferase complex

3 of 3

2.6

2.26

6.46e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0648

Protein biosynthesis

8 of 45

1.85

4.15

4.53e-12

KW-0436

Ligase

9 of 81

1.65

3.44

4.53e-12

KW-0030

Aminoacyl-tRNA synthetase

5 of 20

2.0

3.16

1.09e-07

KW-0067

ATP-binding

9 of 296

1.08

1.35

1.09e-07

KW-0820

tRNA-binding

2 of 11

1.86

0.97

0.0127

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01425

Amidase

2 of 2

2.6

0.92

0.0210

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR045864

Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)

4 of 14

2.06

2.0

0.00010

IPR036928

Amidase signature (AS) superfamily

2 of 2

2.6

0.86

0.0275

IPR023631

Amidase signature domain

2 of 2

2.6

0.86

0.0275

IPR020556

Amidase, conserved site

2 of 2

2.6

0.86

0.0275

IPR000120

Amidase

2 of 2

2.6

0.86

0.0275

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