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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemCPorphyrin biosynthesis protein HemD; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (821 aa)    
Predicted Functional Partners:
KIX15868.1
Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
KIX15929.1
Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.
 0.998
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
 0.985
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.985
hemL
Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.963
KIX15869.1
Cytochrome C biogenesis protein ResC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.907
KIX15560.1
Cytochrome C biogenesis protein ResC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.907
KIX11621.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.900
KIX14027.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.898
KIX12153.1
Catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.895
Your Current Organism:
Dethiosulfatarculus sandiegensis
NCBI taxonomy Id: 1429043
Other names: D. sandiegensis, DSM 100305, Deltaproteobacteria bacterium SPR, Desulfarculus sp. SPR, Dethiosulfatarculus sandiegensis Davidova et al. 2016, JCM 30857, strain SPR
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