STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIX10928.1Acylphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa)    
Predicted Functional Partners:
ligA
NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
       0.800
KIX13813.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.785
KIX14952.1
acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     
 0.670
KIX15908.1
GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.653
KIX11481.1
CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.653
KIX13701.1
Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.618
KIX13124.1
4-hydroxybenzoate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.614
selA
Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
     
 0.607
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.589
KIX14031.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.588
Your Current Organism:
Dethiosulfatarculus sandiegensis
NCBI taxonomy Id: 1429043
Other names: D. sandiegensis, DSM 100305, Deltaproteobacteria bacterium SPR, Desulfarculus sp. SPR, Dethiosulfatarculus sandiegensis Davidova et al. 2016, JCM 30857, strain SPR
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