STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM66373.1hydroxymethylglutaryl-CoA lyase. (287 aa)    
Predicted Functional Partners:
SHM86815.1
methylglutaconyl-CoA hydratase.
 
 
 0.886
SHM90994.1
3-oxoacid CoA-transferase subunit B.
 
 
 0.882
SHM90969.1
3-oxoacid CoA-transferase subunit A.
 
 
 0.881
SHM47284.1
acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.859
SHM55899.1
acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.859
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.845
SHM33688.1
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.841
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.830
SHM80613.1
Acyl-CoA hydrolase.
     
 0.818
SHN03712.1
Acetyl-CoA carboxylase, carboxyltransferase component.
 
 0.818
Your Current Organism:
Salegentibacter salegens
NCBI taxonomy Id: 143223
Other names: ACAM 48, ATCC 51522, CCUG 33447, CIP 104041, DSM 5424, Flavobacterium salegens, LMG 13193, LMG:13193, S. salegens
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.