node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIS41950.1 | SIS65808.1 | SAMN05421766_101770 | SAMN05421766_103189 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.935 |
SIS41950.1 | SIS65820.1 | SAMN05421766_101770 | SAMN05421766_103190 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 5'-nucleotidase, C-terminal domain. | 0.895 |
SIS41950.1 | SIS94375.1 | SAMN05421766_101770 | SAMN05421766_10594 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.949 |
SIS41950.1 | adk | SAMN05421766_101770 | SAMN05421766_104268 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.915 |
SIS41950.1 | apt | SAMN05421766_101770 | SAMN05421766_104563 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.951 |
SIS41950.1 | guaA | SAMN05421766_101770 | SAMN05421766_106140 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.673 |
SIS41950.1 | guaB | SAMN05421766_101770 | SAMN05421766_104635 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.442 |
SIS41950.1 | surE | SAMN05421766_101770 | SAMN05421766_101791 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.867 |
SIS65808.1 | SIS41950.1 | SAMN05421766_103189 | SAMN05421766_101770 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.935 |
SIS65808.1 | SIS65820.1 | SAMN05421766_103189 | SAMN05421766_103190 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase, C-terminal domain. | 0.994 |
SIS65808.1 | SIS83579.1 | SAMN05421766_103189 | SAMN05421766_104263 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 5'(3')-deoxyribonucleotidase. | 0.868 |
SIS65808.1 | SIS94375.1 | SAMN05421766_103189 | SAMN05421766_10594 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.937 |
SIS65808.1 | adk | SAMN05421766_103189 | SAMN05421766_104268 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.882 |
SIS65808.1 | apt | SAMN05421766_103189 | SAMN05421766_104563 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.879 |
SIS65808.1 | guaA | SAMN05421766_103189 | SAMN05421766_106140 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.887 |
SIS65808.1 | guaB | SAMN05421766_103189 | SAMN05421766_104635 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.934 |
SIS65808.1 | purA | SAMN05421766_103189 | SAMN05421766_102402 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.877 |
SIS65808.1 | surE | SAMN05421766_103189 | SAMN05421766_101791 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.879 |
SIS65820.1 | SIS41950.1 | SAMN05421766_103190 | SAMN05421766_101770 | 5'-nucleotidase, C-terminal domain. | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.895 |
SIS65820.1 | SIS65808.1 | SAMN05421766_103190 | SAMN05421766_103189 | 5'-nucleotidase, C-terminal domain. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.994 |