STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (425 aa)    
Predicted Functional Partners:
AKB76939.1
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.998
AKB76984.1
IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase.
 
 0.987
AKB78073.1
Asparagine synthetase (glutamine-hydrolyzing).
 
 
 0.987
AKB79446.1
Cytidine kinase; Belongs to the carbohydrate kinase PfkB family.
  
 0.978
pyrB
Aspartate carbamoyltransferase.
  
 
 0.956
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.949
AKB76491.1
5'-nucleotidase.
 
  
 0.944
surE
5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.931
AKB76658.1
Asparagine synthetase (glutamine-hydrolyzing).
  
 
 0.930
AKB80543.1
Asparagine synthetase (glutamine-hydrolyzing).
  
 
 0.925
Your Current Organism:
Methanosarcina horonobensis
NCBI taxonomy Id: 1434110
Other names: M. horonobensis HB-1 = JCM 15518, Methanosarcina horonobensis HB-1, Methanosarcina horonobensis HB-1 = JCM 15518, Methanosarcina horonobensis JCM 15518, Methanosarcina horonobensis JCM 15518 = HB-1, Methanosarcina sp. HB-1
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