STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMC56640.1FKBP-type peptidyl-prolyl cis-trans isomerase FklB. (145 aa)    
Predicted Functional Partners:
SMC56621.1
Glycine/D-amino acid oxidase.
   
   0.715
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.674
infA
Bacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.645
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
 
    0.631
SMC88598.1
Peptidyl-prolyl cis-trans isomerase A (cyclophilin A).
 
0.622
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
    
 0.610
SMC81524.1
DNA polymerase V.
  
 
   0.500
SMC78316.1
Do/DeqQ family serine protease.
  
 
 0.494
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
    
  0.479
SMC56554.1
Cupin domain-containing protein.
       0.465
Your Current Organism:
Moheibacter sediminis
NCBI taxonomy Id: 1434700
Other names: CGMCC 1.12708, Empedobacter sp. M0116, JCM 19634, M. sediminis, Moheibacter sediminis Zhang et al. 2014, strain M0116
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.