STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parPi_0002747ANK_REP_REGION domain-containing protein. (2039 aa)    
Predicted Functional Partners:
parPi_0002790
SAE2 domain-containing protein.
    
 0.956
parPi_0007696
MPN domain-containing protein.
    
 0.956
parPi_0010043
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.946
parPi_0003140
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
    
 0.943
parPi_0026272
BRCT domain-containing protein.
   
 0.920
parPi_0024231
Uncharacterized protein.
   
 0.920
parPi_0015079
Zinc-hook domain-containing protein.
    
 0.889
parPi_0001475
Tower domain-containing protein.
    
 0.888
parPi_0013888
Uncharacterized protein; Belongs to the RecA family.
  
 0.888
parPi_0020227
BRCC36_C domain-containing protein.
    
 0.867
Your Current Organism:
Paroedura picta
NCBI taxonomy Id: 143630
Other names: P. picta, ZMB 4798
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.