STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parPi_0026326DNA_pol_B domain-containing protein. (226 aa)    
Predicted Functional Partners:
parPi_0010854
Uncharacterized protein.
   
 0.997
parPi_0022928
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
    
 0.995
parPi_0008639
MFS domain-containing protein.
   
 0.991
parPi_0014141
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
 0.991
parPi_0003537
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.989
parPi_0004773
DNA helicase; Belongs to the MCM family.
   
 0.988
parPi_0011428
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.985
parPi_0019669
HORMA domain-containing protein.
    
 0.985
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.984
parPi_0011430
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.984
Your Current Organism:
Paroedura picta
NCBI taxonomy Id: 143630
Other names: P. picta, ZMB 4798
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