STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parPi_0006477Ubiquitin carboxyl-terminal hydrolase. (793 aa)    
Predicted Functional Partners:
parPi_0022305
Uncharacterized protein.
   
 0.986
parPi_0022249
Uncharacterized protein.
   
 0.986
parPi_0009725
Uncharacterized protein.
    
 0.940
parPi_0017858
Uncharacterized protein.
    
 0.927
parPi_0005040
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 0.924
parPi_0018034
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.918
parPi_0013910
Plus3 domain-containing protein.
   
  0.901
parPi_0007399
TPR_REGION domain-containing protein.
   
  0.899
parPi_0003087
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
     
 0.897
parPi_0007916
Uncharacterized protein.
   
 
  0.891
Your Current Organism:
Paroedura picta
NCBI taxonomy Id: 143630
Other names: P. picta, ZMB 4798
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.