STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDM24414.1Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (661 aa)    
Predicted Functional Partners:
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.999
SDL92841.1
DKNYY family protein.
    
 0.990
SDM80574.1
Peptidylprolyl isomerase.
   
 0.983
SDL82247.1
DnaJ domain-containing protein.
   
 0.968
SDL92654.1
DnaJ domain-containing protein.
   
 0.968
SDM04886.1
DnaJ-class molecular chaperone with C-terminal Zn finger domain.
   
 0.968
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
 0.968
SDM76922.1
DnaJ domain-containing protein.
   
 0.968
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.966
SDM01726.1
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.953
Your Current Organism:
Maricaulis salignorans
NCBI taxonomy Id: 144026
Other names: CIP 107439, DSM 16077, LMG 19864, LMG:19864, M. salignorans, Maricaulis salignorans Abraham et al. 2002, Maricaulis sp. MCS18, Marinocaulobacter sp. MCS18, strain MCS 18
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