Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
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Neighborhood
Groups of genes that are frequently observed in each other's genomic neighborhood.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UA08_00059
MFS domain-containing protein. (596 aa)
Predicted Functional Partners:
UA08_03410
Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.
0.496
UA08_09072
MFS domain-containing protein.
0.491
Your Current Organism:
Talaromyces atroroseus
NCBI taxonomy Id: 1441469 Other names: CBS 133442, DTO 178A4, IBT 32470, KAS 3778, T. atroroseus, Talaromyces atroroseus Yilmaz, Frisvad, Houbraken & Samson, 2013