STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
casp6Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (301 aa)    
Predicted Functional Partners:
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.965
LOC103375115
Uncharacterized protein; Belongs to the peptidase C14A family.
   
0.964
LOC103376203
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
0.964
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
0.952
lmna
Lamin A; Belongs to the intermediate filament family.
   
 0.930
ENSSPAP00000002652
Uncharacterized protein; Belongs to the intermediate filament family.
   
 0.928
lmnb1
Lamin B1; Belongs to the intermediate filament family.
   
 0.926
lmnb2
Lamin B2; Belongs to the intermediate filament family.
   
 0.926
actb
Uncharacterized protein.
    
 0.924
LOC103375119
Uncharacterized protein; Belongs to the peptidase C14A family.
   
0.918
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.