STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSSPAP00000002540SAE2 domain-containing protein. (75 aa)    
Predicted Functional Partners:
brca1
Uncharacterized protein.
   
 0.999
mre11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.994
bard1
BRCA1 associated RING domain 1.
    
 0.992
ENSSPAP00000003155
FHA domain-containing protein.
    
 0.991
rad50
RAD50 homolog, double strand break repair protein.
    
 0.991
ENSSPAP00000002276
ANK_REP_REGION domain-containing protein.
    
 0.961
ankrd11
Ankyrin repeat domain 11.
    
 0.961
exo1
Exonuclease 1.
   
 0.958
atm
Non-specific serine/threonine protein kinase.
    
 0.931
sirt6
Sirtuin 6.
   
 0.907
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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