STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (491 aa)    
Predicted Functional Partners:
psenen
Presenilin enhancer, gamma-secretase subunit.
    
 0.991
LOC103368490
APH1B gamma secretase subunit.
   
 0.990
NCSTN
Nicastrin.
   
 0.990
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.975
LOC103353434
Notch receptor 1b.
    
 0.956
LOC103357999
Notch receptor 1a.
    
 0.956
LOC103371495
Uncharacterized protein.
    
 0.955
LOC103364115
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
 0.917
LOC103367163
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
     
 0.911
prkacb
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
 0.911
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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