Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103373247Suppressor of cytokine signaling 3a. (205 aa)    
Predicted Functional Partners:
lepr
Leptin receptor.
    
 0.987
jak1
Tyrosine-protein kinase.
    
 0.981
socs1
Suppressor of cytokine signaling 1a.
   
 
0.976
tyk2
Tyrosine-protein kinase.
    
 0.974
jak2
Tyrosine-protein kinase.
    
 0.974
LOC103366422
Tyrosine-protein kinase.
    
 0.974
socs5
Suppressor of cytokine signaling 5b.
     
 0.968
eloc
Elongin C paralog a; Belongs to the SKP1 family.
    
 0.967
LOC103372658
Uncharacterized protein.
  
  
 
0.961
LOC103359169
Suppressor of cytokine signaling 1b.
     
 
0.960
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
Server load: low (26%) [HD]