STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
platPlasminogen activator, tissue. (582 aa)    
Predicted Functional Partners:
serpine1
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.
  
 0.990
plg
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
  
  
0.866
met
MET proto-oncogene, receptor tyrosine kinase.
    
 0.762
ENSSPAP00000023532
Macrophage stimulating 1 receptor b.
    
 0.762
LOC103360420
Macrophage stimulating 1 receptor a.
    
 0.762
mst1r
Macrophage stimulating 1 receptor b.
    
 0.762
LOC103356278
Protein S100; Belongs to the S-100 family.
   
 0.753
serpine2
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family.
  
 0.727
LOC103365630
Tissue factor pathway inhibitor.
    
 0.717
pdgfc
Platelet derived growth factor c.
    
 0.710
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.