nkx2-5 protein (Stegastes partitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

nkx2-5

NK2 homeobox 5. (318 aa)

Predicted Functional Partners:

mef2b

0.941

gata4

0.926

LOC103367784

0.918

gata5

0.918

gata6

0.916

mef2c

0.890

tbx4

0.883

tbx5

0.883

ENSSPAP00000015290

0.864

mef2a

0.864

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000015290	mef2b	ENSSPAP00000015290	ENSSPAP00000023922	MADS-box domain-containing protein.	Myocyte enhancer factor 2b.	0.893
ENSSPAP00000015290	mef2c	ENSSPAP00000015290	ENSSPAP00000001231	MADS-box domain-containing protein.	Myocyte enhancer factor 2cb.	0.661
ENSSPAP00000015290	nkx2-5	ENSSPAP00000015290	ENSSPAP00000011310	MADS-box domain-containing protein.	NK2 homeobox 5.	0.864
LOC103367784	gata4	ENSSPAP00000010640	ENSSPAP00000006760	T-box transcription factor 5a.	GATA binding protein 4.	0.776
LOC103367784	gata5	ENSSPAP00000010640	ENSSPAP00000017530	T-box transcription factor 5a.	GATA binding protein 5.	0.679
LOC103367784	gata6	ENSSPAP00000010640	ENSSPAP00000024856	T-box transcription factor 5a.	GATA binding protein 6.	0.729
LOC103367784	mef2c	ENSSPAP00000010640	ENSSPAP00000001231	T-box transcription factor 5a.	Myocyte enhancer factor 2cb.	0.495
LOC103367784	nkx2-5	ENSSPAP00000010640	ENSSPAP00000011310	T-box transcription factor 5a.	NK2 homeobox 5.	0.918
gata4	LOC103367784	ENSSPAP00000006760	ENSSPAP00000010640	GATA binding protein 4.	T-box transcription factor 5a.	0.776
gata4	mef2c	ENSSPAP00000006760	ENSSPAP00000001231	GATA binding protein 4.	Myocyte enhancer factor 2cb.	0.539
gata4	nkx2-5	ENSSPAP00000006760	ENSSPAP00000011310	GATA binding protein 4.	NK2 homeobox 5.	0.926
gata4	tbx4	ENSSPAP00000006760	ENSSPAP00000009019	GATA binding protein 4.	T-box transcription factor 4.	0.588
gata4	tbx5	ENSSPAP00000006760	ENSSPAP00000023913	GATA binding protein 4.	Uncharacterized protein.	0.588
gata5	LOC103367784	ENSSPAP00000017530	ENSSPAP00000010640	GATA binding protein 5.	T-box transcription factor 5a.	0.679
gata5	nkx2-5	ENSSPAP00000017530	ENSSPAP00000011310	GATA binding protein 5.	NK2 homeobox 5.	0.918
gata5	tbx4	ENSSPAP00000017530	ENSSPAP00000009019	GATA binding protein 5.	T-box transcription factor 4.	0.588
gata5	tbx5	ENSSPAP00000017530	ENSSPAP00000023913	GATA binding protein 5.	Uncharacterized protein.	0.588
gata6	LOC103367784	ENSSPAP00000024856	ENSSPAP00000010640	GATA binding protein 6.	T-box transcription factor 5a.	0.729
gata6	nkx2-5	ENSSPAP00000024856	ENSSPAP00000011310	GATA binding protein 6.	NK2 homeobox 5.	0.916
gata6	tbx4	ENSSPAP00000024856	ENSSPAP00000009019	GATA binding protein 6.	T-box transcription factor 4.	0.588