STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vav2Vav 2 guanine nucleotide exchange factor. (843 aa)    
Predicted Functional Partners:
rac3
Rac family small GTPase 3b.
   
 0.948
rac2
Uncharacterized protein.
   
 0.948
RAC1
Rac family small GTPase 1.
   
 0.948
LOC103376111
Uncharacterized protein.
   
 0.948
VAV3
Vav guanine nucleotide exchange factor 3.
  
  
 
0.899
VAV1
Vav guanine nucleotide exchange factor 1.
  
  
 
0.899
grb2
Growth factor receptor-bound protein 2b.
    
0.898
blnk
B cell linker.
   
 0.874
syk
Tyrosine-protein kinase.
   
 0.847
zap70
Tyrosine-protein kinase.
   
 0.847
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.