STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103363949Nucleophosmin 1b. (297 aa)    
Predicted Functional Partners:
LOC103357142
Uncharacterized protein.
   
 
 0.920
ncl
Nucleolin.
   
 
 0.920
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.847
LOC103355287
Ribosomal protein L5.
   
 
 0.830
RPL5
Ribosomal protein L5b.
   
 
 0.830
eef1g
Eukaryotic translation elongation factor 1 gamma.
   
 0.819
LOC103366349
Retinoblastoma binding protein 4, like.
   
 0.747
RBBP4
RB binding protein 4, chromatin remodeling factor.
   
 0.747
LOC103357053
RB binding protein 4, chromatin remodeling factor.
   
 0.747
nop58
NOP58 ribonucleoprotein homolog (yeast).
   
  
 0.743
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
Server load: low (24%) [HD]