STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fpgsFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (578 aa)    
Predicted Functional Partners:
LOC103361115
Zgc:153031.
    
 0.943
LOC103362719
Folate gamma-glutamyl hydrolase.
     
 0.936
LOC103357846
Uncharacterized protein.
     
 0.936
tyms
Thymidylate synthetase.
     
 0.929
dhfr
Dihydrofolate reductase.
    
 0.928
LOC103371587
Dihydrofolate reductase.
    
 0.928
mthfd1l
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.
  
 
 0.926
mthfd1
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b.
  
 
 0.926
nudt15
Nudix (nucleoside diphosphate linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family.
  
 
 0.923
mthfd2l
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.
    
 0.918
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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