STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103367454Si:dkey-163m14.2; Belongs to the G-protein coupled receptor 1 family. (439 aa)    
Predicted Functional Partners:
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.996
LOC103352803
Uncharacterized protein.
    
 0.941
LOC103360700
Guanine nucleotide binding protein (G protein), alpha 13b.
    
 0.941
gna12
G protein subunit alpha 12.
    
 0.941
LOC103367698
Uncharacterized protein.
    
 0.901
ENSSPAP00000027994
Coagulation factor II (thrombin) receptor; Belongs to the G-protein coupled receptor 1 family.
  
  
 
0.900
plg
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
    
 0.895
LOC103361005
Uncharacterized protein.
    
 0.882
ENSSPAP00000000430
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.882
LOC103369973
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.873
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.