STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpnHepsin; Belongs to the peptidase S1 family. (425 aa)    
Predicted Functional Partners:
met
MET proto-oncogene, receptor tyrosine kinase.
    
 0.758
ENSSPAP00000023532
Macrophage stimulating 1 receptor b.
    
 0.758
LOC103360420
Macrophage stimulating 1 receptor a.
    
 0.758
mst1r
Macrophage stimulating 1 receptor b.
    
 0.758
hgf
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
  
 
0.715
mst1
Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.
  
 
0.709
LOC103365344
Hepatocyte growth factor a; Belongs to the peptidase S1 family. Plasminogen subfamily.
   
 
0.684
LOC103368660
Serine peptidase inhibitor, Kunitz type 1 b.
    
 0.678
spint1
Serine peptidase inhibitor, Kunitz type 1 a.
    
 0.678
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
  0.671
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.