STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103369890Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B. (634 aa)    
Predicted Functional Partners:
DCAF7
DDB1 and CUL4 associated factor 7.
   
 
 0.945
lin52
Lin-52 DREAM MuvB core complex component.
    
 0.798
lin54
Lin-54 DREAM MuvB core complex component.
   
 0.736
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.699
lin37
Lin-37 DREAM MuvB core complex component.
    
 0.685
lin9
Lin-9 DREAM MuvB core complex component.
    
 0.678
ENSSPAP00000021362
Ring finger protein 169.
    
 
 0.675
ep300
E1A binding protein p300 b.
   
 0.656
LOC103371563
E1A binding protein p300 a.
   
 0.656
crebbp
CREB binding protein a.
   
 0.644
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.