ENSSPAP00000027825 protein (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSSPAP00000027825

CARD domain-containing protein. (98 aa)

Predicted Functional Partners:

rps27a

0.550

zfand4

0.516

tonsl

0.501

ube2l3

0.485

LOC103371291

0.485

LOC103376010

0.485

LOC103371515

0.485

fau

0.484

ENSSPAP00000000804

0.481

ENSSPAP00000002973

0.481

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000000804	ENSSPAP00000027825	ENSSPAP00000000804	ENSSPAP00000027825	Ubiquitin-like domain-containing protein.	CARD domain-containing protein.	0.481
ENSSPAP00000000804	LOC103371291	ENSSPAP00000000804	ENSSPAP00000017262	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.731
ENSSPAP00000000804	LOC103371515	ENSSPAP00000000804	ENSSPAP00000029713	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.599
ENSSPAP00000000804	LOC103376010	ENSSPAP00000000804	ENSSPAP00000019506	Ubiquitin-like domain-containing protein.	P53-induced death domain protein 1.	0.599
ENSSPAP00000000804	fau	ENSSPAP00000000804	ENSSPAP00000000178	Ubiquitin-like domain-containing protein.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.903
ENSSPAP00000000804	rps27a	ENSSPAP00000000804	ENSSPAP00000030287	Ubiquitin-like domain-containing protein.	Ribosomal protein S27a.	0.932
ENSSPAP00000000804	tonsl	ENSSPAP00000000804	ENSSPAP00000024693	Ubiquitin-like domain-containing protein.	Tonsoku-like, DNA repair protein.	0.687
ENSSPAP00000000804	ube2l3	ENSSPAP00000000804	ENSSPAP00000015858	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family.	0.731
ENSSPAP00000000804	zfand4	ENSSPAP00000000804	ENSSPAP00000018463	Ubiquitin-like domain-containing protein.	Zinc finger, AN1-type domain 4.	0.536
ENSSPAP00000002973	ENSSPAP00000027825	ENSSPAP00000002973	ENSSPAP00000027825	Ubiquitin-like domain-containing protein.	CARD domain-containing protein.	0.481
ENSSPAP00000002973	LOC103371291	ENSSPAP00000002973	ENSSPAP00000017262	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.731
ENSSPAP00000002973	LOC103371515	ENSSPAP00000002973	ENSSPAP00000029713	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.599
ENSSPAP00000002973	LOC103376010	ENSSPAP00000002973	ENSSPAP00000019506	Ubiquitin-like domain-containing protein.	P53-induced death domain protein 1.	0.599
ENSSPAP00000002973	fau	ENSSPAP00000002973	ENSSPAP00000000178	Ubiquitin-like domain-containing protein.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.903
ENSSPAP00000002973	rps27a	ENSSPAP00000002973	ENSSPAP00000030287	Ubiquitin-like domain-containing protein.	Ribosomal protein S27a.	0.931
ENSSPAP00000002973	tonsl	ENSSPAP00000002973	ENSSPAP00000024693	Ubiquitin-like domain-containing protein.	Tonsoku-like, DNA repair protein.	0.687
ENSSPAP00000002973	ube2l3	ENSSPAP00000002973	ENSSPAP00000015858	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family.	0.731
ENSSPAP00000002973	zfand4	ENSSPAP00000002973	ENSSPAP00000018463	Ubiquitin-like domain-containing protein.	Zinc finger, AN1-type domain 4.	0.536
ENSSPAP00000027825	ENSSPAP00000000804	ENSSPAP00000027825	ENSSPAP00000000804	CARD domain-containing protein.	Ubiquitin-like domain-containing protein.	0.481
ENSSPAP00000027825	ENSSPAP00000002973	ENSSPAP00000027825	ENSSPAP00000002973	CARD domain-containing protein.	Ubiquitin-like domain-containing protein.	0.481

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

15

average node degree:

2.73

avg. local clustering coefficient:

0.798

expected number of edges:

10

PPI enrichment p-value:

0.096

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016331

Morphogenesis of embryonic epithelium

4 of 107

1.85

1.28

0.0027

GO:0002009

Morphogenesis of an epithelium

5 of 353

1.43

1.06

0.0033

GO:0060670

Branching involved in labyrinthine layer morphogenesis

2 of 8

2.68

1.05

0.0124

GO:0001843

Neural tube closure

3 of 66

1.94

1.01

0.0112

GO:0008544

Epidermis development

4 of 211

1.56

0.96

0.0093

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004252

Serine-type endopeptidase activity

5 of 180

1.72

1.85

6.81e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:12518

MET Receptor Activation, and Delta-catenin binding

5 of 12

2.9

5.05

3.95e-10

CL:12521

MET Receptor Activation

4 of 6

3.1

4.21

2.00e-08

CL:12228

Transmembrane receptor protein tyrosine kinase signaling pathway, and GPVI-mediated activation cascade

6 of 157

1.86

2.92

1.41e-07

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-6806942

MET Receptor Activation

3 of 6

2.98

2.64

1.54e-05

MAP-8852405

Signaling by MST1

2 of 4

2.98

1.38

0.0032

MAP-6806834

Signaling by MET

3 of 78

1.86

1.22

0.0038

MAP-9006934

Signaling by Receptor Tyrosine Kinases

5 of 529

1.25

0.96

0.0032

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0420

Kringle

4 of 15

2.7

3.84

6.24e-08

KW-0720

Serine protease

4 of 94

1.91

2.14

2.85e-05

KW-0721

Serine protease homolog

2 of 2

3.28

2.12

0.00015

KW-1015

Disulfide bond

7 of 1202

1.04

7.41e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01390

SEA domain

2 of 11

2.54

0.75

0.0444

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038178

Kringle superfamily

4 of 15

2.7

3.5

2.90e-07

IPR018056

Kringle, conserved site

4 of 15

2.7

3.5

2.90e-07

IPR000001

Kringle

4 of 15

2.7

3.5

2.90e-07

IPR013806

Kringle-like fold

4 of 31

2.39

2.94

2.16e-06

IPR001254

Serine proteases, trypsin domain

6 of 137

1.92

2.9

2.90e-07

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00130

Kringle domain

4 of 15

2.7

3.83

6.48e-08

SM00020

Trypsin-like serine protease

6 of 138

1.92

3.21

3.49e-08

SM00473

Divergent subfamily of APPLE domains

2 of 3

3.1

1.75

0.00068

SM00059

Fibronectin type 2 domain

2 of 18

2.32

1.09

0.0096

SM00192

Low-density lipoprotein receptor domain class A

2 of 46

1.92

0.71

0.0454

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (14%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About