STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
irak4Interleukin-1 receptor-associated kinase 4. (489 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.997
irak1
Interleukin-1 receptor-associated kinase 1.
   
0.990
TIRAP
TIR domain containing adaptor protein.
   
 0.972
tab1
TGF-beta activated kinase 1/MAP3K7 binding protein 1.
   
 0.961
tab2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.960
LOC103361723
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.951
LOC103367507
TNF receptor-associated factor 6-like.
   
 0.951
LOC103369011
Component of inhibitor of nuclear factor kappa B kinase complex.
  
 
0.941
LOC103357629
TRIF-NTD domain-containing protein.
   
 0.940
LOC103366020
Protein kinase domain-containing protein.
  
 
0.937
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.