phf6 protein (Stegastes partitus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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Textmining

[Homology]

Score

phf6

PHD finger protein 6. (359 aa)

Predicted Functional Partners:

ash2l

0.789

LOC103366349

0.788

RBBP4

0.788

LOC103357053

0.788

rbbp5

0.787

eed

0.725

mphosph8

0.689

dot1l

0.682

setbp1

0.681

prdm5

0.645

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103357053	LOC103366349	ENSSPAP00000027778	ENSSPAP00000014953	RB binding protein 4, chromatin remodeling factor.	Retinoblastoma binding protein 4, like.	0.898
LOC103357053	RBBP4	ENSSPAP00000027778	ENSSPAP00000027234	RB binding protein 4, chromatin remodeling factor.	RB binding protein 4, chromatin remodeling factor.	0.898
LOC103357053	eed	ENSSPAP00000027778	ENSSPAP00000031162	RB binding protein 4, chromatin remodeling factor.	Embryonic ectoderm development.	0.975
LOC103357053	mphosph8	ENSSPAP00000027778	ENSSPAP00000002954	RB binding protein 4, chromatin remodeling factor.	Chromo domain-containing protein.	0.494
LOC103357053	phf6	ENSSPAP00000027778	ENSSPAP00000030215	RB binding protein 4, chromatin remodeling factor.	PHD finger protein 6.	0.788
LOC103357053	prdm5	ENSSPAP00000027778	ENSSPAP00000018391	RB binding protein 4, chromatin remodeling factor.	Zinc finger protein.	0.471
LOC103357053	rbbp5	ENSSPAP00000027778	ENSSPAP00000011281	RB binding protein 4, chromatin remodeling factor.	Retinoblastoma binding protein 5.	0.721
LOC103357053	setbp1	ENSSPAP00000027778	ENSSPAP00000029083	RB binding protein 4, chromatin remodeling factor.	SET binding protein 1.	0.574
LOC103366349	LOC103357053	ENSSPAP00000014953	ENSSPAP00000027778	Retinoblastoma binding protein 4, like.	RB binding protein 4, chromatin remodeling factor.	0.898
LOC103366349	RBBP4	ENSSPAP00000014953	ENSSPAP00000027234	Retinoblastoma binding protein 4, like.	RB binding protein 4, chromatin remodeling factor.	0.898
LOC103366349	eed	ENSSPAP00000014953	ENSSPAP00000031162	Retinoblastoma binding protein 4, like.	Embryonic ectoderm development.	0.975
LOC103366349	mphosph8	ENSSPAP00000014953	ENSSPAP00000002954	Retinoblastoma binding protein 4, like.	Chromo domain-containing protein.	0.494
LOC103366349	phf6	ENSSPAP00000014953	ENSSPAP00000030215	Retinoblastoma binding protein 4, like.	PHD finger protein 6.	0.788
LOC103366349	prdm5	ENSSPAP00000014953	ENSSPAP00000018391	Retinoblastoma binding protein 4, like.	Zinc finger protein.	0.471
LOC103366349	rbbp5	ENSSPAP00000014953	ENSSPAP00000011281	Retinoblastoma binding protein 4, like.	Retinoblastoma binding protein 5.	0.721
LOC103366349	setbp1	ENSSPAP00000014953	ENSSPAP00000029083	Retinoblastoma binding protein 4, like.	SET binding protein 1.	0.574
RBBP4	LOC103357053	ENSSPAP00000027234	ENSSPAP00000027778	RB binding protein 4, chromatin remodeling factor.	RB binding protein 4, chromatin remodeling factor.	0.898
RBBP4	LOC103366349	ENSSPAP00000027234	ENSSPAP00000014953	RB binding protein 4, chromatin remodeling factor.	Retinoblastoma binding protein 4, like.	0.898
RBBP4	eed	ENSSPAP00000027234	ENSSPAP00000031162	RB binding protein 4, chromatin remodeling factor.	Embryonic ectoderm development.	0.975
RBBP4	mphosph8	ENSSPAP00000027234	ENSSPAP00000002954	RB binding protein 4, chromatin remodeling factor.	Chromo domain-containing protein.	0.494

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

38

average node degree:

6.91

avg. local clustering coefficient:

0.887

expected number of edges:

11

PPI enrichment p-value:

9.25e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1903509

Liposaccharide metabolic process

7 of 22

1.97

3.85

8.22e-10

GO:0009312

Oligosaccharide biosynthetic process

5 of 13

2.06

3.08

2.69e-07

GO:0009245

Lipid A biosynthetic process

4 of 9

2.12

2.57

6.31e-06

GO:0016051

Carbohydrate biosynthetic process

7 of 58

1.55

2.37

1.18e-07

GO:0008610

Lipid biosynthetic process

7 of 71

1.47

2.11

2.64e-07

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3328

Polyketide sugar unit biosynthesis, and SIS domain

5 of 7

2.33

3.55

8.77e-08

CL:2416

Oligosaccharide metabolic process

5 of 10

2.17

3.29

1.66e-07

CL:2418

Lipid A biosynthesis

2 of 5

2.07

1.01

0.0124

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00540

Lipopolysaccharide biosynthesis

8 of 21

2.05

5.14

2.67e-13

map00523

Polyketide sugar unit biosynthesis

2 of 4

2.17

1.17

0.0063

map00521

Streptomycin biosynthesis

2 of 8

1.87

0.95

0.0141

map00541

O-Antigen nucleotide sugar biosynthesis

2 of 13

1.66

0.79

0.0261

map01100

Metabolic pathways

11 of 1283

0.41

0.34

0.0022

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0441

Lipid A biosynthesis

4 of 6

2.3

2.82

3.00e-06

KW-0448

Lipopolysaccharide biosynthesis

2 of 3

2.3

1.22

0.0053

KW-0808

Transferase

6 of 404

0.64

0.38

0.0414

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