STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bcl2BCL2 apoptosis regulator b. (228 aa)    
Predicted Functional Partners:
bax
BCL2 associated X, apoptosis regulator a.
    
0.994
becn1
Beclin 1, autophagy related.
    
 0.993
ENSSPAP00000028083
Uncharacterized protein.
    
 0.993
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.982
LOC103357552
Zgc:153993.
    
0.980
bad
BCL2 associated agonist of cell death b.
   
 0.979
bnip3
BCL2 interacting protein 3.
    
 0.964
LOC103357984
Zgc:73226.
    
 0.964
LOC103365897
BH4_2 domain-containing protein.
  
 
0.939
bcl2l1
BCL2 like 1.
    
0.937
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.