STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AJ80_06292BRCT domain-containing protein. (269 aa)    
Predicted Functional Partners:
AJ80_02197
Uncharacterized protein.
    
 0.819
AJ80_01402
Zn(2)-C6 fungal-type domain-containing protein.
    
 0.819
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.772
AJ80_06264
Uncharacterized protein.
    
 0.743
AJ80_01693
DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.
    
 0.743
AJ80_09618
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.742
AJ80_03729
Uncharacterized protein.
    
  0.741
AJ80_00524
Uncharacterized protein.
    
  0.741
AJ80_06799
Ubiquitin-like domain-containing protein.
    
 0.714
AJ80_02989
SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.713
Your Current Organism:
Polytolypa hystricis
NCBI taxonomy Id: 1447883
Other names: P. hystricis UAMH7299, Polytolypa hystricis Ph7299, Polytolypa hystricis UAMH7299
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.