A0A2T2NK75 protein (Corynespora cassiicola) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

A0A2T2NK75

TGc domain-containing protein. (658 aa)

Predicted Functional Partners:

A0A2T2NSQ1

0.816

A0A2T2NYF5

0.643

A0A2T2NES7

0.618

A0A2T2NKN1

0.601

NOP7

0.586

A0A2T2NKZ0

0.543

ERB1

0.520

A0A2T2NBJ7

0.497

A0A2T2P6R7

0.489

A0A2T2N1N3

0.467

Your Current Organism:

Corynespora cassiicola

NCBI taxonomy Id: 1448308
Other names: C. cassiicola Philippines, Corynespora cassiicola INRA-Clermont Ferrand, Corynespora cassiicola Philippines

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A2T2N1N3	A0A2T2NBJ7	A0A2T2N1N3	A0A2T2NBJ7	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	CLP1_P domain-containing protein.	0.754
A0A2T2N1N3	A0A2T2NES7	A0A2T2N1N3	A0A2T2NES7	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	rRNA processing protein Ipi1.	0.990
A0A2T2N1N3	A0A2T2NK75	A0A2T2N1N3	A0A2T2NK75	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	TGc domain-containing protein.	0.467
A0A2T2N1N3	A0A2T2NYF5	A0A2T2N1N3	A0A2T2NYF5	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	WD domain-containing protein.	0.993
A0A2T2N1N3	A0A2T2P6R7	A0A2T2N1N3	A0A2T2P6R7	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	CP-type G domain-containing protein.	0.998
A0A2T2N1N3	ERB1	A0A2T2N1N3	A0A2T2P560	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.991
A0A2T2N1N3	NOP7	A0A2T2N1N3	A0A2T2N5I2	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.997
A0A2T2NBJ7	A0A2T2N1N3	A0A2T2NBJ7	A0A2T2N1N3	CLP1_P domain-containing protein.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.754
A0A2T2NBJ7	A0A2T2NES7	A0A2T2NBJ7	A0A2T2NES7	CLP1_P domain-containing protein.	rRNA processing protein Ipi1.	0.970
A0A2T2NBJ7	A0A2T2NK75	A0A2T2NBJ7	A0A2T2NK75	CLP1_P domain-containing protein.	TGc domain-containing protein.	0.497
A0A2T2NBJ7	A0A2T2NYF5	A0A2T2NBJ7	A0A2T2NYF5	CLP1_P domain-containing protein.	WD domain-containing protein.	0.992
A0A2T2NBJ7	A0A2T2P6R7	A0A2T2NBJ7	A0A2T2P6R7	CLP1_P domain-containing protein.	CP-type G domain-containing protein.	0.767
A0A2T2NBJ7	ERB1	A0A2T2NBJ7	A0A2T2P560	CLP1_P domain-containing protein.	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.906
A0A2T2NBJ7	NOP7	A0A2T2NBJ7	A0A2T2N5I2	CLP1_P domain-containing protein.	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.832
A0A2T2NES7	A0A2T2N1N3	A0A2T2NES7	A0A2T2N1N3	rRNA processing protein Ipi1.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.990
A0A2T2NES7	A0A2T2NBJ7	A0A2T2NES7	A0A2T2NBJ7	rRNA processing protein Ipi1.	CLP1_P domain-containing protein.	0.970
A0A2T2NES7	A0A2T2NK75	A0A2T2NES7	A0A2T2NK75	rRNA processing protein Ipi1.	TGc domain-containing protein.	0.618
A0A2T2NES7	A0A2T2NYF5	A0A2T2NES7	A0A2T2NYF5	rRNA processing protein Ipi1.	WD domain-containing protein.	0.999
A0A2T2NES7	A0A2T2P6R7	A0A2T2NES7	A0A2T2P6R7	rRNA processing protein Ipi1.	CP-type G domain-containing protein.	0.969
A0A2T2NES7	ERB1	A0A2T2NES7	A0A2T2P560	rRNA processing protein Ipi1.	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.903

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Network Stats

number of nodes:

11

number of edges:

13

average node degree:

2.36

avg. local clustering coefficient:

0.915

expected number of edges:

11

PPI enrichment p-value:

0.26

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009401

Phosphoenolpyruvate-dependent sugar phosphotransferase system

4 of 5

2.48

2.84

4.13e-06

GO:0006355

Regulation of transcription, DNA-templated

7 of 236

1.05

1.03

0.00010

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008982

protein-N(PI)-phosphohistidine-sugar phosphotransferase activity

2 of 2

2.58

1.03

0.0131

GO:0003677

DNA binding

7 of 353

0.87

0.63

0.0058

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2526

Periplasmic binding protein-like domain, and Phosphotransferase system (PTS)

10 of 17

2.35

8.19

1.85e-19

CL:2529

Phosphotransferase system (PTS), and Periplasmic binding protein-like domain

6 of 10

2.35

4.96

6.17e-11

CL:2425

Carbohydrate metabolic process, and Transcriptional regulator LacI/GalR-like, sensor domain

11 of 85

1.69

4.25

2.34e-16

CL:2531

Phosphotransferase system (PTS)

4 of 5

2.48

3.37

3.50e-07

CL:2550

Amine-lyase activity, and LacI-type HTH domain

3 of 5

2.35

2.18

7.18e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02060

Phosphotransferase system (PTS)

4 of 7

2.33

3.05

1.11e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0032993

protein-DNA complex

7 of 59

1.65

2.77

1.64e-08

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0598

Phosphotransferase system

3 of 3

2.58

1.52e-05

KW-0805

Transcription regulation

7 of 113

1.37

1.82

9.29e-07

KW-0238

DNA-binding

7 of 178

1.17

1.35

6.45e-06

KW-0762

Sugar transport

2 of 4

2.28

1.27

0.0042

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13377

Periplasmic binding protein-like domain

6 of 8

2.45

4.97

1.16e-10

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR046335

Transcriptional regulator LacI/GalR-like, sensor domain

7 of 9

2.47

5.85

1.34e-12

IPR028082

Periplasmic binding protein-like I

7 of 12

2.34

5.49

2.95e-12

IPR000843

LacI-type HTH domain

5 of 8

2.37

3.81

2.89e-08

IPR010982

Lambda repressor-like, DNA-binding domain superfamily

5 of 26

1.86

2.48

2.80e-06

IPR033532

Arabinose metabolism transcriptional repressor, ligand-binding domain

2 of 2

2.58

1.06

0.0116

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00354

Helix_turn _helix lactose operon repressor

5 of 8

2.37

4.09

6.95e-09

SM00345

Helix_turn_helix gluconate operon transcriptional repressor

2 of 12

1.8

0.76

0.0347

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