A0A2T2NQ11 protein (Corynespora cassiicola) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A2T2NQ11

Cytochrome P450. (302 aa)

Predicted Functional Partners:

A0A2T2P2C1

0.671

A0A2T2N756

0.634

A0A2T2MZ56

0.564

A0A2T2NFQ3

0.543

A0A2T2NJE7

0.506

A0A2T2PA11

0.506

A0A2T2NEG1

0.461

A0A2T2PCH3

0.461

A0A2T2MZW7

0.454

A0A2T2N1V3

0.454

Your Current Organism:

Corynespora cassiicola

NCBI taxonomy Id: 1448308
Other names: C. cassiicola Philippines, Corynespora cassiicola INRA-Clermont Ferrand, Corynespora cassiicola Philippines

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2T2MZ56	A0A2T2MZW7	Beta-ketoacyl synthase.	NAD(P)-binding protein.	0.490
A0A2T2MZ56	A0A2T2N1V3	Beta-ketoacyl synthase.	Uncharacterized protein.	0.490
A0A2T2MZ56	A0A2T2N756	Beta-ketoacyl synthase.	Tryptophan synthase.	0.930
A0A2T2MZ56	A0A2T2NFQ3	Beta-ketoacyl synthase.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.962
A0A2T2MZ56	A0A2T2NQ11	Beta-ketoacyl synthase.	Cytochrome P450.	0.564
A0A2T2MZW7	A0A2T2MZ56	NAD(P)-binding protein.	Beta-ketoacyl synthase.	0.490
A0A2T2MZW7	A0A2T2N756	NAD(P)-binding protein.	Tryptophan synthase.	0.893
A0A2T2MZW7	A0A2T2NFQ3	NAD(P)-binding protein.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.872
A0A2T2MZW7	A0A2T2NQ11	NAD(P)-binding protein.	Cytochrome P450.	0.454
A0A2T2N1V3	A0A2T2MZ56	Uncharacterized protein.	Beta-ketoacyl synthase.	0.490
A0A2T2N1V3	A0A2T2N756	Uncharacterized protein.	Tryptophan synthase.	0.893
A0A2T2N1V3	A0A2T2NFQ3	Uncharacterized protein.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.872
A0A2T2N1V3	A0A2T2NQ11	Uncharacterized protein.	Cytochrome P450.	0.454
A0A2T2N756	A0A2T2MZ56	Tryptophan synthase.	Beta-ketoacyl synthase.	0.930
A0A2T2N756	A0A2T2MZW7	Tryptophan synthase.	NAD(P)-binding protein.	0.893
A0A2T2N756	A0A2T2N1V3	Tryptophan synthase.	Uncharacterized protein.	0.893
A0A2T2N756	A0A2T2NQ11	Tryptophan synthase.	Cytochrome P450.	0.634
A0A2T2N756	A0A2T2P2C1	Tryptophan synthase.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.800
A0A2T2NEG1	A0A2T2NQ11	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	Cytochrome P450.	0.461
A0A2T2NFQ3	A0A2T2MZ56	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Beta-ketoacyl synthase.	0.962

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.841

expected number of edges:

13

PPI enrichment p-value:

0.00128

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006172

ADP biosynthetic process

2 of 2

3.04

1.56

0.0015

GO:0009179

Purine ribonucleoside diphosphate metabolic process

3 of 19

2.24

1.51

0.0014

GO:0009167

Purine ribonucleoside monophosphate metabolic process

3 of 20

2.22

1.51

0.0014

GO:0032386

Regulation of intracellular transport

3 of 25

2.12

1.49

0.0014

GO:0003400

Regulation of COPII vesicle coating

2 of 4

2.74

1.44

0.0024

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050145

Nucleoside monophosphate kinase activity

3 of 6

2.74

2.27

6.86e-05

GO:0004017

Adenylate kinase activity

2 of 3

2.87

1.41

0.0028

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6770

Multivesicular body sorting pathway, and Calpain-like thiol protease family.

6 of 31

2.33

4.58

4.21e-10

CL:6820

Calpain-like thiol protease family., and Regulation of COPII vesicle coating

4 of 6

2.87

3.97

4.53e-08

CL:12808

Metabolism of nucleotides, and Biosynthesis of maresins

3 of 56

1.77

1.05

0.0078

CL:6793

Multivesicular body sorting pathway

2 of 10

2.35

0.95

0.0176

CL:12890

Deoxyribonucleotide biosynthetic process, and Nucleoside monophosphate kinase activity

2 of 15

2.17

0.87

0.0245

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04626

Plant-pathogen interaction

2 of 5

2.65

1.62

0.0011

map00230

Purine metabolism

4 of 100

1.65

1.6

0.00023

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-499943

Interconversion of nucleotide di- and triphosphates

3 of 25

2.12

1.46

0.0016

MAP-15869

Metabolism of nucleotides

3 of 68

1.69

0.92

0.0140

MAP-9668328

Sealing of the nuclear envelope (NE) by ESCRT-III

2 of 13

2.23

0.88

0.0239

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0042584

Chromaffin granule membrane

2 of 3

2.87

1.19

0.0071

GOCC:0005935

Cellular bud neck

2 of 18

2.09

0.85

0.0258

GOCC:0043227

Membrane-bounded organelle

9 of 3197

0.49

0.33

0.0258

GOCC:0043229

Intracellular organelle

10 of 4076

0.43

0.3

0.0258

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13207

AAA domain

2 of 2

3.04

1.31

0.0044

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036193

Adenylate kinase, active site lid domain superfamily

2 of 2

3.04

1.06

0.0125

IPR007862

Adenylate kinase, active site lid domain

2 of 2

3.04

1.06

0.0125

IPR006259

Adenylate kinase subfamily

2 of 2

3.04

1.06

0.0125

IPR033690

Adenylate kinase, conserved site

2 of 3

2.87

1.05

0.0125

IPR000850

Adenylate kinase/UMP-CMP kinase

2 of 3

2.87

1.05

0.0125

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00054

EF-hand, calcium binding motif

2 of 15

2.17

0.81

0.0317

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About