A0A2T2NVD6 protein (Corynespora cassiicola) - STRING interaction network

Nodes:

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:

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[Homology]

Score

A0A2T2NVD6

Cryptochrome. (666 aa)

Predicted Functional Partners:

A0A2T2NWZ5

0.839

A0A2T2NQH4

0.794

A0A2T2NHL6

0.594

A0A2T2NL15

0.594

A0A2T2NV83

0.594

A0A2T2NVA7

0.594

A0A2T2P679

0.594

A0A2T2P0H0

0.553

A0A2T2ND74

0.532

A0A2T2NJ11

0.499

Your Current Organism:

Corynespora cassiicola

NCBI taxonomy Id: 1448308
Other names: C. cassiicola Philippines, Corynespora cassiicola INRA-Clermont Ferrand, Corynespora cassiicola Philippines

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2T2ND74	A0A2T2NVD6	Uncharacterized protein.	Cryptochrome.	0.532
A0A2T2NHL6	A0A2T2NQH4	Uncharacterized protein.	Timeless-domain-containing protein.	0.582
A0A2T2NHL6	A0A2T2NVD6	Uncharacterized protein.	Cryptochrome.	0.594
A0A2T2NHL6	A0A2T2NWZ5	Uncharacterized protein.	Casein kinase I; Belongs to the protein kinase superfamily.	0.746
A0A2T2NJ11	A0A2T2NQH4	RNI-like protein.	Timeless-domain-containing protein.	0.419
A0A2T2NJ11	A0A2T2NVD6	RNI-like protein.	Cryptochrome.	0.499
A0A2T2NL15	A0A2T2NQH4	Uncharacterized protein.	Timeless-domain-containing protein.	0.582
A0A2T2NL15	A0A2T2NVD6	Uncharacterized protein.	Cryptochrome.	0.594
A0A2T2NL15	A0A2T2NWZ5	Uncharacterized protein.	Casein kinase I; Belongs to the protein kinase superfamily.	0.746
A0A2T2NQH4	A0A2T2NHL6	Timeless-domain-containing protein.	Uncharacterized protein.	0.582
A0A2T2NQH4	A0A2T2NJ11	Timeless-domain-containing protein.	RNI-like protein.	0.419
A0A2T2NQH4	A0A2T2NL15	Timeless-domain-containing protein.	Uncharacterized protein.	0.582
A0A2T2NQH4	A0A2T2NV83	Timeless-domain-containing protein.	Uncharacterized protein.	0.582
A0A2T2NQH4	A0A2T2NVA7	Timeless-domain-containing protein.	PAS domain-containing protein.	0.582
A0A2T2NQH4	A0A2T2NVD6	Timeless-domain-containing protein.	Cryptochrome.	0.794
A0A2T2NQH4	A0A2T2NWZ5	Timeless-domain-containing protein.	Casein kinase I; Belongs to the protein kinase superfamily.	0.901
A0A2T2NQH4	A0A2T2P679	Timeless-domain-containing protein.	Uncharacterized protein.	0.582
A0A2T2NV83	A0A2T2NQH4	Uncharacterized protein.	Timeless-domain-containing protein.	0.582
A0A2T2NV83	A0A2T2NVA7	Uncharacterized protein.	PAS domain-containing protein.	0.947
A0A2T2NV83	A0A2T2NVD6	Uncharacterized protein.	Cryptochrome.	0.594

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.874

expected number of edges:

11

PPI enrichment p-value:

4.69e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009116

Nucleoside metabolic process

6 of 12

2.19

3.97

4.21e-09

GO:0042278

Purine nucleoside metabolic process

3 of 3

2.49

2.1

0.00012

GO:0034655

Nucleobase-containing compound catabolic process

4 of 21

1.77

1.78

0.00013

GO:0009119

Ribonucleoside metabolic process

3 of 8

2.06

1.75

0.00036

GO:0055086

Nucleobase-containing small molecule metabolic process

8 of 130

1.28

1.71

3.20e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016763

Pentosyltransferase activity

5 of 18

1.93

2.58

2.37e-06

GO:0106130

Purine phosphoribosyltransferase activity

2 of 2

2.49

1.07

0.0111

GO:0004731

Purine-nucleoside phosphorylase activity

2 of 2

2.49

1.07

0.0111

GO:0019239

Deaminase activity

2 of 8

1.89

0.69

0.0496

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

9 of 951

0.46

0.31

0.0334

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1517

Phosphoribosyl transferase domain, and Nucleobase transport

4 of 5

2.39

2.74

5.71e-06

CL:1105

UMP salvage, and Pyrimidine nucleoside metabolic process

3 of 6

2.19

1.77

0.00040

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

9 of 74

1.57

3.12

1.13e-11

map00240

Pyrimidine metabolism

6 of 48

1.58

2.35

2.80e-07

map00760

Nicotinate and nicotinamide metabolism

4 of 24

1.71

1.91

4.13e-05

map01110

Biosynthesis of secondary metabolites

6 of 348

0.72

0.51

0.0076

map01100

Metabolic pathways

11 of 986

0.54

0.47

4.13e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-168249

Innate Immune System

3 of 21

1.64

1.42

0.00074

MAP-168256

Immune System

3 of 24

1.58

1.38

0.00074

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0660

Purine salvage

2 of 2

2.49

1.24

0.0052

KW-0328

Glycosyltransferase

5 of 78

1.29

1.17

0.00058

KW-0808

Transferase

6 of 367

0.7

0.43

0.0294

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00156

Phosphoribosyl transferase domain

3 of 6

2.19

1.59

0.00094

PF01048

Phosphorylase superfamily

2 of 3

2.31

0.91

0.0212

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR029057

Phosphoribosyltransferase-like

3 of 9

2.01

1.15

0.0063

IPR000836

Phosphoribosyltransferase domain

3 of 9

2.01

1.15

0.0063

IPR035994

Nucleoside phosphorylase superfamily

2 of 3

2.31

0.78

0.0365

IPR000845

Nucleoside phosphorylase domain

2 of 3

2.31

0.78

0.0365

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