A0A2T2NXE4 protein (Corynespora cassiicola) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A2T2NXE4

Uncharacterized protein. (629 aa)

Predicted Functional Partners:

A0A2T2N4Z5

0.809

A0A2T2P6N7

0.809

A0A2T2PD29

0.809

A0A2T2P2C1

0.777

A0A2T2N7F1

0.548

A0A2T2N4P3

0.528

A0A2T2N7I7

0.528

A0A2T2NB23

0.528

A0A2T2NCH2

0.528

A0A2T2NNX6

0.528

Your Current Organism:

Corynespora cassiicola

NCBI taxonomy Id: 1448308
Other names: C. cassiicola Philippines, Corynespora cassiicola INRA-Clermont Ferrand, Corynespora cassiicola Philippines

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2T2N4P3	A0A2T2N7F1	rRNA-processing protein-like protein FCF1.	U3 snoRNP protein Utp20.	0.999
A0A2T2N4P3	A0A2T2N7I7	rRNA-processing protein-like protein FCF1.	WD40 repeat-like protein.	0.999
A0A2T2N4P3	A0A2T2NB23	rRNA-processing protein-like protein FCF1.	Nucleolar essential protein-like protein 1.	0.999
A0A2T2N4P3	A0A2T2NCH2	rRNA-processing protein-like protein FCF1.	CBF-domain-containing protein.	0.999
A0A2T2N4P3	A0A2T2NNX6	rRNA-processing protein-like protein FCF1.	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	0.999
A0A2T2N4P3	A0A2T2NXE4	rRNA-processing protein-like protein FCF1.	Uncharacterized protein.	0.528
A0A2T2N4Z5	A0A2T2NXE4	GDPD-domain-containing protein.	Uncharacterized protein.	0.809
A0A2T2N4Z5	A0A2T2P2C1	GDPD-domain-containing protein.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.428
A0A2T2N4Z5	A0A2T2P6N7	GDPD-domain-containing protein.	GDPD-domain-containing protein.	0.923
A0A2T2N4Z5	A0A2T2PD29	GDPD-domain-containing protein.	Glycerophosphoryl diester phosphodiesterase.	0.922
A0A2T2N7F1	A0A2T2N4P3	U3 snoRNP protein Utp20.	rRNA-processing protein-like protein FCF1.	0.999
A0A2T2N7F1	A0A2T2N7I7	U3 snoRNP protein Utp20.	WD40 repeat-like protein.	0.999
A0A2T2N7F1	A0A2T2NB23	U3 snoRNP protein Utp20.	Nucleolar essential protein-like protein 1.	0.999
A0A2T2N7F1	A0A2T2NCH2	U3 snoRNP protein Utp20.	CBF-domain-containing protein.	0.999
A0A2T2N7F1	A0A2T2NNX6	U3 snoRNP protein Utp20.	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	0.999
A0A2T2N7F1	A0A2T2NXE4	U3 snoRNP protein Utp20.	Uncharacterized protein.	0.548
A0A2T2N7I7	A0A2T2N4P3	WD40 repeat-like protein.	rRNA-processing protein-like protein FCF1.	0.999
A0A2T2N7I7	A0A2T2N7F1	WD40 repeat-like protein.	U3 snoRNP protein Utp20.	0.999
A0A2T2N7I7	A0A2T2NB23	WD40 repeat-like protein.	Nucleolar essential protein-like protein 1.	0.999
A0A2T2N7I7	A0A2T2NCH2	WD40 repeat-like protein.	CBF-domain-containing protein.	0.999

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.913

expected number of edges:

10

PPI enrichment p-value:

1.83e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006730

One-carbon metabolic process

6 of 10

1.84

2.72

4.76e-07

GO:0035999

Tetrahydrofolate interconversion

5 of 7

1.92

2.62

1.68e-06

GO:0009086

Methionine biosynthetic process

4 of 5

1.97

2.28

1.68e-05

GO:1901607

Alpha-amino acid biosynthetic process

7 of 24

1.53

2.18

4.76e-07

GO:0009067

Aspartate family amino acid biosynthetic process

5 of 12

1.68

2.14

6.43e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016646

Oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor

3 of 5

1.84

1.01

0.0107

GO:0106313

Methylenetetrahydrofolate reductase NADPH activity

2 of 2

2.06

0.72

0.0465

GO:0106312

Methylenetetrahydrofolate reductase NADH activity

2 of 2

2.06

0.72

0.0465

GO:0004372

Glycine hydroxymethyltransferase activity

2 of 2

2.06

0.72

0.0465

GO:0016741

Transferase activity, transferring one-carbon groups

4 of 40

1.06

0.54

0.0465

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:695

Tetrahydrofolate interconversion

4 of 5

1.97

1.95

0.00010

CL:666

Purine biosynthesis, and Pteridine-containing compound metabolic process

5 of 22

1.42

1.43

0.00017

CL:2137

Cysteine and methionine metabolism

3 of 5

1.84

1.36

0.0018

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00670

One carbon pool by folate

6 of 13

1.73

2.66

1.80e-07

map01230

Biosynthesis of amino acids

5 of 30

1.28

1.29

0.00016

map00260

Glycine, serine and threonine metabolism

3 of 9

1.59

1.27

0.0015

map01200

Carbon metabolism

5 of 37

1.19

1.14

0.00027

map00460

Cyanoamino acid metabolism

2 of 3

1.89

1.06

0.0086

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005829

Cytosol

9 of 166

0.8

0.72

9.60e-05

GOCC:0005737

Cytoplasm

10 of 359

0.51

0.4

0.0024

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0554

One-carbon metabolism

4 of 6

1.89

1.93

8.94e-05

KW-0028

Amino-acid biosynthesis

3 of 9

1.59

1.01

0.0074

KW-0489

Methyltransferase

4 of 29

1.2

0.83

0.0074

KW-0663

Pyridoxal phosphate

2 of 5

1.66

0.68

0.0468

KW-0560

Oxidoreductase

3 of 28

1.09

0.55

0.0468

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (16%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About