| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ETX29924.1 | ETX30431.1 | RISW2_19945 | RISW2_12235 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.706 |
| ETX29924.1 | ETX30490.1 | RISW2_19945 | RISW2_12545 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.923 |
| ETX29924.1 | fhs | RISW2_19945 | RISW2_16560 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the formate--tetrahydrofolate ligase family. | 0.904 |
| ETX29924.1 | folD | RISW2_19945 | RISW2_16555 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.969 |
| ETX29924.1 | gcvH | RISW2_19945 | RISW2_19940 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| ETX29924.1 | gcvP | RISW2_19945 | RISW2_19935 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
| ETX29924.1 | glyA | RISW2_19945 | RISW2_02500 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.998 |
| ETX29924.1 | purH | RISW2_19945 | RISW2_12335 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.889 |
| ETX29924.1 | purN | RISW2_19945 | RISW2_14645 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.878 |
| ETX29924.1 | purU | RISW2_19945 | RISW2_04320 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.868 |
| ETX30431.1 | ETX29924.1 | RISW2_12235 | RISW2_19945 | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.706 |
| ETX30431.1 | ETX30490.1 | RISW2_12235 | RISW2_12545 | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.861 |
| ETX30431.1 | fhs | RISW2_12235 | RISW2_16560 | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the formate--tetrahydrofolate ligase family. | 0.914 |
| ETX30431.1 | folD | RISW2_12235 | RISW2_16555 | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.967 |
| ETX30431.1 | gcvH | RISW2_12235 | RISW2_19940 | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.457 |
| ETX30431.1 | glyA | RISW2_12235 | RISW2_02500 | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.906 |
| ETX30431.1 | purH | RISW2_12235 | RISW2_12335 | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.873 |
| ETX30431.1 | purN | RISW2_12235 | RISW2_14645 | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.909 |
| ETX30431.1 | purU | RISW2_12235 | RISW2_04320 | Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.461 |
| ETX30490.1 | ETX29924.1 | RISW2_12545 | RISW2_19945 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
