STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AJF85614.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)    
Predicted Functional Partners:
pksN
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.955
pksN-2
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.954
pksM
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.943
srfAC
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.894
AJF85153.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.887
dhbF
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.843
pksR
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.820
dltA-5
Alanine-phosphoribitol ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent A [...]
    
 0.818
AJF85615.1
Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.816
fabF-2
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.716
Your Current Organism:
Bacillus atrophaeus
NCBI taxonomy Id: 1452
Other names: ATCC 49337, B. atrophaeus, Bacillus atriphaeus, Bacillus sp. S2 BC-2, Bacillus subtilis DSM 2277, Bacillus subtilis DSM 675, CCUG 28524, CIP 107159, DSM 7264, IFO 15539, JCM 9070, LMG 16797, LMG:16797, NBRC 15539, NRRL NRS-213
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