AMK13517.1 protein (methanogenic archaeon mixed)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AMK13517.1

RNase P subunit RPR2. (105 aa)

Predicted Functional Partners:

AMK13228.1

0.999

AMK13359.1

0.999

AMK13371.1

0.999

AMK14243.1

0.999

AMK14244.1

0.999

AMK14305.1

0.999

AMK14510.1

0.999

AMK14518.1

0.993

AMK14361.1

0.902

AMK13174.1

0.858

Your Current Organism:

methanogenic archaeon mixed

NCBI taxonomy Id: 1452364
Other names: m. archaeon mixed culture ISO4-G1, methanogenic archaeon mixed culture ISO4-G1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMK13174.1	AMK13228.1	AUP07_0114	AUP07_0168	Ribosomal protein S2P Rps2p.	PIN domain-containing protein.	0.999
AMK13174.1	AMK13371.1	AUP07_0114	AUP07_0315	Ribosomal protein S2P Rps2p.	Ribosomal protein S5P Rps5p.	0.999
AMK13174.1	AMK13517.1	AUP07_0114	AUP07_0461	Ribosomal protein S2P Rps2p.	RNase P subunit RPR2.	0.858
AMK13174.1	AMK14243.1	AUP07_0114	AUP07_1202	Ribosomal protein S2P Rps2p.	Ribosomal protein S11P Rps11p.	0.999
AMK13174.1	AMK14244.1	AUP07_0114	AUP07_1203	Ribosomal protein S2P Rps2p.	Ribosomal protein S4P Rps4p.	0.999
AMK13174.1	AMK14361.1	AUP07_0114	AUP07_1324	Ribosomal protein S2P Rps2p.	Serine/threonine protein kinase RIO1.	0.970
AMK13174.1	AMK14510.1	AUP07_0114	AUP07_1477	Ribosomal protein S2P Rps2p.	Ribosomal protein S6e Rps6e.	0.999
AMK13174.1	AMK14518.1	AUP07_0114	AUP07_1485	Ribosomal protein S2P Rps2p.	Ribosomal protein L7Ae Rpl7ae.	0.999
AMK13228.1	AMK13174.1	AUP07_0168	AUP07_0114	PIN domain-containing protein.	Ribosomal protein S2P Rps2p.	0.999
AMK13228.1	AMK13371.1	AUP07_0168	AUP07_0315	PIN domain-containing protein.	Ribosomal protein S5P Rps5p.	0.999
AMK13228.1	AMK13517.1	AUP07_0168	AUP07_0461	PIN domain-containing protein.	RNase P subunit RPR2.	0.999
AMK13228.1	AMK14243.1	AUP07_0168	AUP07_1202	PIN domain-containing protein.	Ribosomal protein S11P Rps11p.	0.999
AMK13228.1	AMK14244.1	AUP07_0168	AUP07_1203	PIN domain-containing protein.	Ribosomal protein S4P Rps4p.	0.999
AMK13228.1	AMK14361.1	AUP07_0168	AUP07_1324	PIN domain-containing protein.	Serine/threonine protein kinase RIO1.	0.999
AMK13228.1	AMK14510.1	AUP07_0168	AUP07_1477	PIN domain-containing protein.	Ribosomal protein S6e Rps6e.	0.999
AMK13228.1	AMK14518.1	AUP07_0168	AUP07_1485	PIN domain-containing protein.	Ribosomal protein L7Ae Rpl7ae.	0.999
AMK13359.1	AMK13371.1	AUP07_0303	AUP07_0315	Ribonuclease P subunit P29.	Ribosomal protein S5P Rps5p.	0.807
AMK13359.1	AMK13517.1	AUP07_0303	AUP07_0461	Ribonuclease P subunit P29.	RNase P subunit RPR2.	0.999
AMK13359.1	AMK14305.1	AUP07_0303	AUP07_1268	Ribonuclease P subunit P29.	Hypothetical protein.	0.985
AMK13359.1	AMK14510.1	AUP07_0303	AUP07_1477	Ribonuclease P subunit P29.	Ribosomal protein S6e Rps6e.	0.768

page 1 of 5

Network Stats

number of nodes:

3

number of edges:

2

average node degree:

1.33

avg. local clustering coefficient:

0.667

expected number of edges:

2

PPI enrichment p-value:

0.531

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0098660

Inorganic ion transmembrane transport

5 of 75

1.48

1.64

4.67e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046933

Proton-transporting ATP synthase activity, rotational mechanism

4 of 9

2.3

2.78

3.71e-06

GO:0005216

Ion channel activity

5 of 29

1.89

2.47

3.71e-06

GO:0015075

Ion transmembrane transporter activity

6 of 106

1.41

1.76

5.17e-06

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

2 of 2

2.65

1.52

0.0017

GO:0022853

Active ion transmembrane transporter activity

3 of 37

1.56

1.14

0.0032

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016469

Proton-transporting two-sector ATPase complex

5 of 11

2.31

3.91

1.31e-08

GO:0045259

Proton-transporting ATP synthase complex

4 of 10

2.26

3.01

1.06e-06

GO:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

3 of 5

2.43

2.48e-05

GO:0033177

Proton-transporting two-sector ATPase complex, proton-transporting domain

2 of 6

2.18

1.47

0.0016

GO:0031676

Plasma membrane-derived thylakoid membrane

4 of 98

1.27

1.07

0.0012

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1356

ATP synthesis, and Adenylate kinase activity

4 of 12

2.18

2.34

2.39e-05

CL:1360

ATP synthesis

3 of 7

2.29

1.75

0.00049

CL:3455

Mixed, incl. Cation/H+ exchanger, and Potassium ion transport

3 of 24

1.75

1.05

0.0078

CL:3493

MgtC family, and Cation transporter/ATPase, N-terminus

2 of 5

2.26

1.04

0.0119

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

6 of 71

1.58

2.26

6.23e-07

map00195

Photosynthesis

4 of 58

1.49

1.39

0.00043

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016469

Proton-transporting two-sector ATPase complex

5 of 12

2.27

3.69

3.28e-08

GOCC:0045259

Proton-transporting ATP synthase complex

4 of 11

2.22

2.81

2.57e-06

GOCC:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

3 of 5

2.43

2.31

4.39e-05

GOCC:0033177

Proton-transporting two-sector ATPase complex, proton-transporting domain

2 of 7

2.11

1.12

0.0078

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0066

ATP synthesis

4 of 9

2.3

2.9

2.12e-06

KW-0375

Hydrogen ion transport

4 of 10

2.26

2.87

2.12e-06

KW-0139

CF(1)

3 of 5

2.43

2.36

3.45e-05

KW-0793

Thylakoid

4 of 79

1.36

1.17

0.0010

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02874

ATP synthase alpha/beta family, beta-barrel domain

2 of 2

2.65

0.96

0.0181

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036121

ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily

2 of 2

2.65

0.74

0.0456

IPR020003

ATPase, alpha/beta subunit, nucleotide-binding domain, active site

2 of 2

2.65

0.74

0.0456

IPR004100

ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain

2 of 2

2.65

0.74

0.0456

IPR000194

ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain

2 of 2

2.65

0.74

0.0456

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About