STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCM56237.1Putative methylthioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_01678}; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (309 aa)    
Predicted Functional Partners:
mtiP
S-methyl-5'-thioinosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
 
 
 0.974
SCM56235.1
Putative protein MJ1093; sp|Q58493|Y1093_METJA;evalue=3e-074; PctID=50.93; score=278.
       0.804
fucA
Catalyzes the cleavage of L-fuculose 1-phosphate to glycerone phosphate and L-lactaldehyde. (S)-lactaldehyde. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 1 zinc ion per subunit; lactaldehyde and glycerone phosphate from L-fucose: step 3/3. subfamily; sp|P44777|FUCA_HAEIN;evalue=5e-024; PctID=36.61; score=110.
  
  
 0.801
pheS
Phenylalanine-tRNA ligase alpha subunit {ECO:0000255|HAMAP-Rule:MF_00282}; sp|O26837|SYFA_METTH;evalue=0.0; PctID=83.33; score=865; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
 
    0.733
SCM56233.1
Putative protein MJ0802; sp|Q58212|Y802_METJA;evalue=4e-010; PctID=34.75; score=64.3.
       0.710
SCM56230.1
Putative protein MJ0404; sp|Q57847|Y404_METJA;evalue=2e-041; PctID=58.74; score=167.
       0.700
SCM56232.1
Putative protein MJ0800; sp|Q58210|Y800_METJA;evalue=3e-156; PctID=68.06; score=551.
       0.700
SCM56228.1
Putative protein MJ0498; sp|Q57921|Y498_METJA;evalue=6e-015; PctID=37.61; score=79.7.
       0.653
hpt
Hypoxanthine/guanine phosphoribosyltransferase {ECO:0000255|HAMAP-Rule:MF_01467}; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
  
    0.652
SCM56226.1
UPF0288 protein; sp|O27893|Y1865_METTH;evalue=0.0; PctID=79.10; score=840; Belongs to the UPF0288 family.
       0.587
Your Current Organism:
Methanothermobacter wolfeii
NCBI taxonomy Id: 145261
Other names: ATCC 43096, DSM 2970, JCM 14652, M. wolfeii, Methanobacterium wolfei, Methanobacterium wolfeii, Methanothermobacter wolfei, NBRC 100332, OCM 154
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