STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nudt17Nucleoside diphosphate-linked moiety X motif 17; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence=; Sequence=AAH87815.1; Type=Erroneous initiation; Evidence=; sp|Q5M8V2|NUD17_XENTR;evalue=5e-007; PctID=37.33; score=53.5. (154 aa)    
Predicted Functional Partners:
cshA
DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'-and 3'-directions, has RNA-dependent ATPase activity. subfamily; sp|Q4L7W0|CSHA_STAHJ;evalue=6e-090; PctID=40.57; score=331; Belongs to the DEAD box helicase family.
  
 0.873
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase {ECO:0000255|HAMAP-Rule:MF_00351}; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.873
dapF
Diaminopimelate epimerase {ECO:0000255|HAMAP-Rule:MF_00197}; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
   
 
 0.826
SCM57084.1
Thermonuclease {ECO:0000313|EMBL:AAB85000,1}; tr|O26594|O26594_METTH;evalue=9e-062; PctID=70.11; score=241.
    
 0.729
rrp41
Exosome complex component Rrp41 {ECO:0000255|HAMAP-Rule:MF_00591}; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
 
  
 0.727
rrp42
Exosome complex component Rrp42 {ECO:0000255|HAMAP-Rule:MF_00622}; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
    
 0.702
csl4
Exosome complex component Csl4 {ECO:0000255|HAMAP-Rule:MF_00975}; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
   
 0.702
rrp4
Exosome complex component Rrp4 {ECO:0000255|HAMAP-Rule:MF_00623}; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.
    
 0.644
SCM56481.1
Sensory transduction histidine kinase {ECO:0000313|EMBL:BAM69337,1}; tr|T2GGQ9|T2GGQ9_9EURY;evalue=1e-117; PctID=61.71; score=429.
       0.563
rpl44e
50S ribosomal protein L44e {ECO:0000255|HAMAP-Rule:MF_01476}; Binds to the 23S rRNA.
  
 
 0.499
Your Current Organism:
Methanothermobacter wolfeii
NCBI taxonomy Id: 145261
Other names: ATCC 43096, DSM 2970, JCM 14652, M. wolfeii, Methanobacterium wolfei, Methanobacterium wolfeii, Methanothermobacter wolfei, NBRC 100332, OCM 154
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.